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Fenquizone

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Chemical compound Pharmaceutical compound
Fenquizone
Clinical data
ATC code
Identifiers
IUPAC name
  • 7-chloro-4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.039.702 Edit this at Wikidata
Chemical and physical data
FormulaC14H12ClN3O3S
Molar mass337.78 g·mol
3D model (JSmol)
SMILES
  • O=S(=O)(c3c(Cl)cc2c(C(=O)NC(c1ccccc1)N2)c3)N
InChI
  • InChI=1S/C14H12ClN3O3S/c15-10-7-11-9(6-12(10)22(16,20)21)14(19)18-13(17-11)8-4-2-1-3-5-8/h1-7,13,17H,(H,18,19)(H2,16,20,21)
  • Key:DBDTUXMDTSTPQZ-UHFFFAOYSA-N
  (verify)

Fenquizone (INN) is a diuretic, part of the class of low-ceiling sulfonamide diuretics. Fenquizone is used primarily in the treatment of oedema and hypertension.

See also

References

  1. Ferrando C, Foy JM, Pratt CN, Purvis JR (April 1981). "On the pharmacological actions of a diuretic, fenquizone, with particular reference to its site of action". The Journal of Pharmacy and Pharmacology. 33 (4): 219–22. doi:10.1111/j.2042-7158.1981.tb13761.x. PMID 6115903.
  2. "Fenquizone". Drug Information from MIMS. Thailand.
Diuretics (C03)
Sulfonamides
(and etacrynic acid)
CA inhibitors (at PT)
Loop (Na-K-Cl at AL)
Thiazides (Na-Cl at DCT,
Calcium-sparing)
Thiazide-likes (primarily DCT)
Potassium-sparing (at CD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT, DL)
Vasopressin receptor inhibitors
(DCT and CD)
Other
Combination products


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