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Tagaturonate reductase

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Enzyme
tagaturonate reductase
Identifiers
EC no.1.1.1.58
CAS no.9028-45-9
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BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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Tagaturonate reductase (EC 1.1.1.58) is an enzyme that catalyzes the chemical reaction

D-altronate + NAD {\displaystyle \rightleftharpoons } D-tagaturonate + NADH + H

Thus, the two substrates of this enzyme are D-altronate and NAD, whereas its 3 products are D-tagaturonate, NADH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is D-altronate:NAD 3-oxidoreductase. Other names in common use include altronic oxidoreductase, altronate oxidoreductase, TagUAR, altronate dehydrogenase, and D-tagaturonate reductase. This enzyme participates in pentose and glucuronate interconversions.

References

  • Hickman J, Ashwell G (1960). "Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D-mannonic acid dehyrogenases in Escherichia coli". J. Biol. Chem. 235: 1566–1570.
Oxidoreductases: alcohol oxidoreductases (EC 1.1)
1.1.1: NAD/NADP acceptor
1.1.2: cytochrome acceptor
1.1.3: oxygen acceptor
1.1.4: disulfide as acceptor
1.1.5: quinone/similar acceptor
1.1.99: other acceptors
Enzymes
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