Suppressor-inducer T cell - Misplaced Pages

Suppressor-inducer T cells are a specific subset of CD4 T helper cells that "induce" CD8 cytotoxic T cells to become "suppressor" cells. Suppressor T cells are also known as CD25–Foxp3 regulatory T cells (nTregs), and reduce inflammation.

References

Negoro T, Iinuma F, Watanabe M (February 1996). "Cellular induction mechanism of CD8+ suppressor T cells by DMBA and TPA: formation of CD4+ suppressor-inducer T cells". Cell. Immunol. 167 (2): 216–23. doi:10.1006/cimm.1996.0029. PMID 8603430.
Shevach EM, DiPaolo RA, Andersson J, Zhao DM, Stephens GL, Thornton AM (August 2006). "The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells". Immunol. Rev. 212: 60–73. doi:10.1111/j.0105-2896.2006.00415.x. PMID 16903906. S2CID 1711208.
Mottet C, Golshayan D (November 2007). "CD4+CD25+Foxp3+ regulatory T cells: from basic research to potential therapeutic use". Swiss Med Wkly. 137 (45–46): 625–34. doi:10.4414/smw.2007.11916. PMID 18027108. S2CID 41378647.

Thymocyte αβ (Cytotoxic CD8 Helper CD4 / T_FH / T_h3 / T_h17 / Regulatory) Naïve Memory T cell T_CM T_EM T_RM T_VM
Innate-like T cells	Natural killer T cell γδ Mucosal associated invariant T cell

NK cells	Cytokine-induced killer cell Lymphokine-activated killer cell Null cell Adaptive NK cell Uterine natural killer cells
Type 1 innate lymphoid cells Type 2 innate lymphoid cells Nuocytes Type 3 innate lymphoid cells LTi cells

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