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The Ministry of Health and Sanitation (Krio: Ministri fɔ Wɛlbɔdi ɛn Sɛnitɛshɔn) is the health ministry of Sierra Leone. As of 2021, the Health Minister is Dr. Austin H. Demby. Their offices are located on the fourth floor of the Youyi Building, Brookfields, Freetown.
As of 2014, the Ministry of Health and Sanitation is engaged in a campaign against the Ebola virus epidemic in West Africa, in which Sierra Leone was one of the most seriously affected countries.