Saxby is an English surname. Notable people with the surname include:
- Alf Saxby (1897–1966), English footballer
- Edward Saxby (1616–1658), English Puritan soldier
- Henry Saxby (1836–1873), English ornithologist
- John Saxby (1821–1913), British engineer and railway pioneer
- Kerry Saxby (born 1961), Australian race walker
- Robin Saxby (born 1947), British businessman
- Selaine Saxby (born 1970), British politician
- Stephen Martin Saxby (1804–1883), English meteorologist and naval officer
- George Saxby Penfold (1769–1846), a Church of England clergyman
Fictional characters:
- Bert Saxby, from James Bond
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