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ST2-PT (Single Transition-to-single Transition Polarization Transfer) is a method of sensitivity enhancement in NMR spectroscopy, developed by K.V. Pervushin, G. Wider, and K. Wüthrich in 1998. This method affords a √2 sensitivity enhancement for kinetically stable amide 15N–1H groups in proteins.

References

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1. Pervushin, K. V.; Wider, G.; Wüthrich, K. (1998). "Single transition-to-single transition polarization transfer (ST2-PT) in -TROSY". Journal of biomolecular NMR.

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