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PRCD
Identifiers
Aliases	PRCD, RP36, progressive rod-cone degeneration, photoreceptor disc component
External IDs	OMIM: 610598; MGI: 3649529; HomoloGene: 135617; GeneCards: PRCD; OMA:PRCD - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q25.1 Start 76,527,586 bp End 76,553,578 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11 E2|11 Start 116,544,360 bp End 116,559,215 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum C1 segment substantia nigra Brodmann area 9 Hypothalamus right auricle cardiac muscle tissue of right atrium canal of the cervix right frontal lobe corpus callosum Top expressed in neural layer of retina retinal pigment epithelium Epithelium of choroid plexus epithelium of lens iris ciliary body adrenal gland embryo ovary left lung lobe More reference expression data BioGPS n/a
Gene ontology Molecular function opsin binding Cellular component photoreceptor outer segment cytoplasm extracellular region endoplasmic reticulum Golgi apparatus photoreceptor outer segment membrane membrane cell projection Biological process response to stimulus visual perception Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 768206 100038570 Ensembl ENSG00000214140 ENSMUSG00000075410 UniProt Q00LT1 Q00LT2 RefSeq (mRNA) NM_001077620 NM_001163318 RefSeq (protein) NP_001071088 NP_001156790 Location (UCSC) Chr 17: 76.53 – 76.55 Mb Chr 11: 116.54 – 116.56 Mb PubMed search
Wikidata
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Progressive rod-cone degeneration is a protein in humans that is encoded by the PRCD gene.

This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. .

References

1. ^ GRCh38: Ensembl release 89: ENSG00000214140 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000075410 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Progressive rod-cone degeneration". Retrieved 2012-11-28.

Further reading

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