Misplaced Pages

Osler's node

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
(Redirected from Osler's nodes) Painful raised skin lesions of the hands and feet Not to be confused with Janeway lesion. For other Osler's signs, see Osler's sign (disambiguation). Medical condition
Osler's node
Osler's lesions found on the hand and fingers of a 43-year-old male with subacute bacterial endocarditis
Differential diagnosisinfective endocarditis

Osler's nodes are painful, red, raised lesions found on the hands and feet. They are associated with a number of conditions, including infective endocarditis, and are caused by immune complex deposition. Their presence is one definition of Osler's sign.

Causes

Osler's nodes result from the deposition of immune complexes. The resulting inflammatory response leads to swelling, redness, and pain that characterize these lesions.

The nodes are commonly indicative of subacute bacterial endocarditis. 10–25% of endocarditis patients will have Osler's nodes. Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender.

Osler's nodes can also be seen in

Etymology

Osler's nodes are named after Sir William Osler who described them in the early twentieth century. He described them as "ephemeral spots of a painful nodular erythema, chiefly in the skin of the hands and feet."

References

  1. "Osler sign" at Dorland's Medical Dictionary
  2. ^ Farrior, JB; Silverman, ME (August 1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis" (PDF). Chest. 70 (2): 239–43. doi:10.1378/chest.70.2.239. PMID 947688.
  3. "Osler nodes" at Dorland's Medical Dictionary
  4. "Endocarditis". The Lecturio Medical Concept Library. Retrieved 19 July 2021.
  5. synd/1702 at Who Named It?
  6. Osler, W (1908–1909). "Chronic infectious endocarditis". Quarterly Journal of Medicine. 2. Oxford: 219–230.
  7. Parashar K, Daveluy S. "Osler's Node and Janeway Lesions". National Center for Biotechnology Information, U.S. National Library of Medicine. Retrieved 19 July 2021.
Signs and symptoms relating to the circulatory system
Chest pain
Auscultation
Pulse
Other
Shock
Cardiovascular disease
Aortic insufficiency
Other endocardium
Pericardium
Other
Vascular disease
Arterial
Venous
Categories:
Osler's node Add topic