Mycoredoxin | |||||||||
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Identifiers | |||||||||
EC no. | 1.20.4.3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Mycoredoxin (EC 1.20.4.3, Mrx1, MrxI) is an enzyme with systematic name arseno-mycothiol:mycoredoxin oxidoreductase. This enzyme catalyses the following chemical reaction
- arseno-mycothiol + mycoredoxin arsenite + mycothiol-mycoredoxin disulfide
Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate.
References
- Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J (May 2009). "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". The Journal of Biological Chemistry. 284 (22): 15107–16. doi:10.1074/jbc.m900877200. PMC 2685692. PMID 19286650.
External links
- Mycoredoxin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Other oxidoreductases (EC 1.15–1.21) | |
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1.15: Acting on superoxide as acceptor | |
1.16: Oxidizing metal ions | |
1.17: Acting on CH or CH2 groups | |
1.18: Acting on iron–sulfur proteins as donors | |
1.19: Acting on reduced flavodoxin as donor | |
1.20: Acting on phosphorus or arsenic in donors | |
1.21: Acting on X-H and Y-H to form an X-Y bond |
Enzymes | |
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Regulation | |
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