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Mycoredoxin

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Class of enzymes
Mycoredoxin
Identifiers
EC no.1.20.4.3
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Mycoredoxin (EC 1.20.4.3, Mrx1, MrxI) is an enzyme with systematic name arseno-mycothiol:mycoredoxin oxidoreductase. This enzyme catalyses the following chemical reaction

arseno-mycothiol + mycoredoxin {\displaystyle \rightleftharpoons } arsenite + mycothiol-mycoredoxin disulfide

Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate.

References

  1. Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J (May 2009). "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". The Journal of Biological Chemistry. 284 (22): 15107–16. doi:10.1074/jbc.m900877200. PMC 2685692. PMID 19286650.

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Other oxidoreductases (EC 1.15–1.21)
1.15: Acting on superoxide as acceptor
1.16: Oxidizing metal ions
1.17: Acting on CH or CH2 groups
1.18: Acting on iron–sulfur proteins as donors
1.19: Acting on reduced flavodoxin as donor
1.20: Acting on phosphorus or arsenic in donors
1.21: Acting on X-H and Y-H to form an X-Y bond
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