Methylketobemidone - Misplaced Pages

Chemical compound Pharmaceutical compound

Methylketobemidone
Clinical data

Routes of administration	?
ATC code	none
Legal status
Legal status	?
Identifiers
IUPAC name 1-ethanone
CAS Number	64058-44-2
PubChem CID	47168
ChemSpider	42930
UNII	2K855U2UGA
CompTox Dashboard (EPA)	DTXSID80214224
Chemical and physical data
Formula	C₁₄H₁₉NO₂
Molar mass	233.311 g·mol
3D model (JSmol)	Interactive image
SMILES O=C(C2(c1cccc(O)c1)CCN(C)CC2)C
InChI InChI=1S/C14H19NO2/c1-11(16)14(6-8-15(2)9-7-14)12-4-3-5-13(17)10-12/h3-5,10,17H,6-9H2,1-2H3 Key:RNAGZQQIHXIDQH-UHFFFAOYSA-N
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Methylketobemidone is an opioid analgesic that is an analogue of ketobemidone. It was developed in the 1950s during research into analogues of pethidine and was assessed by the United Nations Office on Drugs and Crime but was not included on the list of drugs under international control, probably because it was not used in medicine or widely available.

Methylketobemidone is so named because it is the methyl ketone analogue of bemidone (hydroxypethidine). The more commonly used ethyl ketone ("ethylketobemidone") is simply called ketobemidone, as it is the only drug of this family to have been marketed.

Presumably methylketobemidone produces similar effects to pethidine, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.