Kate O'Brien may refer to:
- Kate O'Brien (novelist) (1897–1974), Irish novelist and playwright
- Kate O'Brien (cyclist) (born 1988), Canadian track cyclist and bobsledder
- Kate Cruise O'Brien (1948–1998), Irish writer
- Kate O'Brien (The Drew Carey Show), a character from The Drew Carey Show
See also
- Catherine O'Brien (disambiguation)
- Cathy O'Brien (disambiguation)
- Kate O'Brian, founder of O'Media Strategies
- Katie O'Brien (born 1986), British professional tennis player
- Katy O'Brien (Fair City character), from the Irish television series Fair City
Topics referred to by the same termThis disambiguation page lists articles about people with the same name. If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: