A fifth wheel is a coupling that provides a link between the trailer and a truck (or a tractor unit).
Fifth wheel may also refer to:
- Fifth-wheel trailer, a type of travel trailer that is a variant of the tractor-trailer version
- Fifth wheel (Brooks Walker), an invention designed to aid parking cars
- Fifth Wheel Truck Stops, a truck stop chain across Southern Ontario, Canada
- The 5th Wheel, an American reality dating show
- The Fifth Wheel (film), a 2013 comedy-drama film
- "Fifth Wheel", a song by Avail from their 1998 album Over the James
- An idiom meaning "an extra and unnecessary person or thing"
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