Dysostosis - Misplaced Pages

Bone developmental disorders affecting ossification Medical condition

Dysostosis
Specialty	Medical genetics

A dysostosis (from Ancient Greek δῠσ- (dys-) 'bad, difficult' and ὀστέον (ostéon) 'bone') is a disorder of the development of bone, in particular affecting ossification. Examples include craniofacial dysostosis, Klippel–Feil syndrome, and Rubinstein–Taybi syndrome.

It is one of the two categories of constitutional disorders of bone (the other being osteochondrodysplasia). When the disorder involves the joint between two bones, the term synostosis is often used.

References

"dysostosis" at Dorland's Medical Dictionary
Offiah AC, Hall CM (March 2003). "Radiological diagnosis of the constitutional disorders of bone. As easy as A, B, C?". Pediatr Radiol. 33 (3): 153–61. doi:10.1007/s00247-002-0855-8. PMID 12612812. S2CID 22503835.

External links

Classification	D MeSH: D004413 DiseasesDB: 31424 SNOMED CT: 109420003
External resources	Orphanet: 364559

Congenital malformations and deformations of musculoskeletal system / musculoskeletal abnormality

Appendicular
limb / dysmelia

Arms

clavicle / shoulder	Cleidocranial dysostosis Sprengel's deformity Wallis–Zieff–Goldblatt syndrome
hand deformity	Madelung's deformity Clinodactyly Oligodactyly Polydactyly

Leg

hip	Hip dislocation / Hip dysplasia Upington disease Coxa valga Coxa vara
knee	Genu valgum Genu varum Genu recurvatum Discoid meniscus Congenital patellar dislocation Congenital knee dislocation
foot deformity	varus Club foot Pigeon toe valgus Flat feet Pes cavus Rocker bottom foot Hammer toe

Either / both

fingers and toes	Polydactyly / Syndactyly Webbed toes Arachnodactyly Cenani–Lenz syndactylism Ectrodactyly Brachydactyly Stub thumb
reduction deficits / limb	Acheiropodia Ectromelia Phocomelia Amelia Hemimelia
multiple joints	Arthrogryposis Larsen syndrome RAPADILINO syndrome

Axial

Skull and face

Craniosynostosis	Scaphocephaly Oxycephaly Trigonocephaly
Craniofacial dysostosis	Crouzon syndrome Hypertelorism Hallermann–Streiff syndrome Oto-palato-digital syndrome Treacher Collins syndrome
other	Macrocephaly Platybasia Craniodiaphyseal dysplasia Dolichocephaly Greig cephalopolysyndactyly syndrome Plagiocephaly Saddle nose

Vertebral column

Thoracic skeleton

ribs:	Cervical Bifid
sternum:	Pectus excavatum Pectus carinatum
other:	Poland syndrome

This article about a disease of musculoskeletal and connective tissue is a stub. You can help Misplaced Pages by expanding it.

Categories: