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Complement 4 deficiency

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Medical condition

Complement 4 deficiency
Specialty	Immunology

Complement tests
C4 (C)	FB (A)	C3	CH50	Conditions
·	↓	↓	↓	PSG, C3 NeF AA
↓	·	↓	·	HAE, C4D
·	·	·	↓	TCPD
↓	·/↓	↓	↓	SLE
↑	↑	↑	↑	inflammation

Complement 4 deficiency is a genetic condition affecting complement component 4.

It can present with lupus-like symptoms.

References

Parija (2009). Textbook of Microbiology & Immunology. Elsevier India. pp. 125–. ISBN 978-81-312-2163-1. Retrieved 13 November 2010.
David L. Rimoin; J. Michael Connor; Reed E. Pyeritz; Bruce R. Korf (15 December 2006). Principles and Practice of Medical Genetics: Continually Updated Online Reference. Elsevier Health Sciences. pp. 1860–. ISBN 978-0-443-06870-6. Retrieved 13 November 2010.

External links

Classification	D OMIM: 120820 DiseasesDB: 1873

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Lymphoid and complement disorders causing immunodeficiency

Antibody/humoral
(B)

Hypogammaglobulinemia	X-linked agammaglobulinemia Transient hypogammaglobulinemia of infancy
Dysgammaglobulinemia	IgA deficiency IgG deficiency IgM deficiency Hyper IgM syndrome (1 2 3 4 5) Wiskott–Aldrich syndrome Hyper-IgE syndrome
Other	Common variable immunodeficiency ICF syndrome

T cell deficiency
(T)

thymic hypoplasia: hypoparathyroid (Di George's syndrome)
euparathyroid (Nezelof syndrome
Ataxia–telangiectasia)

peripheral: Purine nucleoside phosphorylase deficiency

Hyper IgM syndrome (1)

Severe combined
(B+T)

x-linked: X-SCID
autosomal: Adenosine deaminase deficiency
Omenn syndrome
ZAP70 deficiency
Bare lymphocyte syndrome

HIV/AIDS

Leukopenia:
Lymphocytopenia

Idiopathic CD4+ lymphocytopenia

Complement
deficiency

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