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BMY-7378

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(Redirected from BMY 7378) Chemical compound Pharmaceutical compound
BMY-7378
Identifiers
IUPAC name
  • 8-(2-ethyl)-8-azaspirodecane-7,9-dione
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H31N3O3
Molar mass385.508 g·mol
3D model (JSmol)
SMILES
  • C4CCCC4(CC1=O)CC(=O)N1CCN3CCN(CC3)c2ccccc2OC
InChI
  • InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3
  • Key:AYYCFGDXLUPJAQ-UHFFFAOYSA-N
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BMY-7,378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist.

References

  1. Goetz AS, King HK, Ward SD, True TA, Rimele TJ, Saussy DL (January 1995). "BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors". European Journal of Pharmacology. 272 (2–3): R5–6. doi:10.1016/0014-2999(94)00751-R. PMID 7713154.
Adrenergic receptor modulators
α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists
Serotonin receptor modulators
5-HT1
5-HT1A
5-HT1B
5-HT1D
5-HT1E
5-HT1F
5-HT2
5-HT2A
5-HT2B
5-HT2C
5-HT37
5-HT3
5-HT4
5-HT5A
5-HT6
5-HT7


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