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ARL8B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2AL7
Identifiers
Aliases	ARL8B, ARL10C, Gie1, ADP ribosylation factor like GTPase 8B
External IDs	OMIM: 616596; MGI: 1914416; HomoloGene: 10056; GeneCards: ARL8B; OMA:ARL8B - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3p26.1 Start 5,122,249 bp End 5,180,911 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 E2 Start 108,760,060 bp End 108,802,239 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus Brodmann area 23 lateral nuclear group of thalamus postcentral gyrus amniotic fluid Brodmann area 46 Pons orbitofrontal cortex gingival epithelium entorhinal cortex Top expressed in dentate gyrus of hippocampal formation granule cell superior frontal gyrus muscle of thigh subiculum tail of embryo anterior amygdaloid area olfactory tubercle ventral tegmental area dorsomedial hypothalamic nucleus prefrontal cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GDP binding alpha-tubulin binding GTP binding GTPase activity beta-tubulin binding protein binding Cellular component cytoplasm endosome membrane late endosome membrane spindle intracellular anatomical structure midbody spindle midzone lysosome extracellular exosome cytoskeleton lysosomal membrane vacuolar membrane axon synapse axon cytoplasm cell junction cell projection Biological process chromosome segregation small GTPase mediated signal transduction cell division cell cycle lysosome localization anterograde axonal transport protein transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55207 67166 Ensembl ENSG00000134108 ENSMUSG00000030105 UniProt Q9NVJ2 Q9CQW2 RefSeq (mRNA) NM_018184 NM_026011 RefSeq (protein) NP_060654 NP_080287 Location (UCSC) Chr 3: 5.12 – 5.18 Mb Chr 6: 108.76 – 108.8 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

ADP-ribosylation factor-like protein 8B is a protein that in humans is encoded by the ARL8B gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000134108 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000030105 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
6. "Entrez Gene: ARL8B ADP-ribosylation factor-like 8B".

External links

• Human ARL8B genome location and ARL8B gene details page in the UCSC Genome Browser.

Further reading

• Bagshaw RD, Callahan JW, Mahuran DJ (2006). "The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes". Biochem. Biophys. Res. Commun. 344 (4): 1186–91. doi:10.1016/j.bbrc.2006.03.221. PMID 16650381.
• Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility". J. Cell Sci. 119 (Pt 8): 1494–503. doi:10.1242/jcs.02958. PMID 16537643.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells" (PDF). Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788. Archived from the original (PDF) on 2019-02-24.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Okai T, Araki Y, Tada M, et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation". J. Cell Sci. 117 (Pt 20): 4705–15. doi:10.1242/jcs.01347. PMID 15331635.
• Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein". J. Biol. Chem. 279 (17): 17126–33. doi:10.1074/jbc.M310097200. PMID 14871887.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

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