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Pethidine intermediate A

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Pethidine intermediate A
Clinical data
Routes of
administration
N/A
ATC code
  • none
Legal status
Legal status
Identifiers
IUPAC name
  • 1-methyl-4-phenylpiperidine-4-carbonitrile
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.020.771 Edit this at Wikidata
Chemical and physical data
FormulaC13H16N2
Molar mass200.28 g/mol g·mol

Pethidine intermediate A is a 4-phenylpiperidine derivative that is a precursor to the opioid analgesic drug pethidine (meperidine). It is not known to have any analgesic activity in its own right, however other derivatives of pethidine with a 4-cyano group in place of the carboxylate ethyl ester have been found to be active, so pethidine intermediate A might also show opioid effects.

See also

References

  1. Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML. Synthesis and Biological Evaluation of Meperidine Analogues at Monoamine Transporters. Journal of Medicinal Chemistry. 2005; 48:1336-1343.
Opioid receptor modulators
μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others
  • Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)
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