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Clinical data | |
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Routes of administration | Oral |
Legal status | |
Legal status |
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Pharmacokinetic data | |
Bioavailability | 65 to 80% |
Protein binding | < 4% |
Metabolism | To apricitabine triphosphate |
Elimination half-life | 6 to 7 hours (triphosphate) |
Excretion | Renal |
Identifiers | |
IUPAC name
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CAS Number | |
PubChem CID | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C8H11N3O3S |
Molar mass | 229.256 g/mol g·mol |
Apricitabine (INN, codenamed AVX754 and SPD754) is an experimental nucleoside reverse transcriptase inhibitor (NRTI).
It was first developed by BioChem Pharma (where it was called BCH10618). BioChem Pharma was then sold the Shire Pharmaceuticals (where the drug was called SPD754). Shire then sold the rights to develop the drug to Avexa, an Australian pharmaceutical company.
References
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