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Apricitabine

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Pharmaceutical compound
Apricitabine
Identifiers
IUPAC name
  • 4-amino-1-pyrimidin-2(1H)-one
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC8H11N3O3S
Molar mass229.256 g/mol g·mol

Apricitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI).

It was first developed by BioChem Pharma (where it was called BCH10618). BioChem Pharma was then sold the Shire Pharmaceuticals (where the drug was called SPD754). Shire then sold the rights to develop the drug to Avexa, an Australian pharmaceutical company.

References

  1. AIDSmeds.com - apricitabine
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Antiviral drugs: antiretroviral drugs used against HIV (primarily J05)
Capsid inhibitors
Entry/fusion inhibitors
(Discovery and development)
Integrase inhibitors
(Integrase strand transfer inhibitors (INSTI))
Maturation inhibitors
Protease Inhibitors (PI)
(Discovery and development)
1 generation
2 generation
Reverse-transcriptase
inhibitors
(RTIs)
Nucleoside and
nucleotide (NRTI)
Non-nucleoside (NNRTI)
(Discovery and development)
1 generation
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Combined formulations
Pharmacokinetic boosters
Experimental agents
Uncoating inhibitors
Transcription inhibitors
Translation inhibitors
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Failed agents
°DHHS recommended initial regimen options. Formerly or rarely used agent.
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