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Amylocaine: Difference between revisions

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Revision as of 19:16, 6 August 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{chembox}} (changes to verified fields - updated 'DrugBank_Ref', 'UNII_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report [[Wikipedia_talk:WikiProject_Che← Previous edit Revision as of 02:22, 9 August 2011 edit undoCheMoBot (talk | contribs)Bots141,565 edits Updating {{chembox}} (no changed fields - added verified revid - updated 'DrugBank_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report [[Wikipedia_talk:WikiProject_CNext edit →
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{{chembox {{chembox
⚫ | verifiedrevid = 443390192
| Verifiedfields = changed
⚫ | verifiedrevid = 396290733
|ImageFile=Amylocaine.png |ImageFile=Amylocaine.png
|ImageSize=200px |ImageSize=200px
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 10312 | ChemSpiderID = 10312
| KEGG_Ref = {{keggcite|changed|kegg}} | KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07454 | KEGG = D07454
| InChI = 1/C14H21NO2/c1-5-14(2,11-15(3)4)17-13(16)12-9-7-6-8-10-12/h6-10H,5,11H2,1-4H3 | InChI = 1/C14H21NO2/c1-5-14(2,11-15(3)4)17-13(16)12-9-7-6-8-10-12/h6-10H,5,11H2,1-4H3
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| CASNo=644-26-8 | CASNo=644-26-8
| PubChem=10767 | PubChem=10767
| UNII_Ref = {{fdacite|changed|FDA}} | UNII_Ref = {{fdacite|correct|FDA}}
| UNII = QRW683O56T | UNII = QRW683O56T
| SMILES = O=C(OC(C)(CC)CN(C)C)c1ccccc1 | SMILES = O=C(OC(C)(CC)CN(C)C)c1ccccc1

Revision as of 02:22, 9 August 2011

Amylocaine
Names
IUPAC name benzoic acid ester
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.010.375 Edit this at Wikidata
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C14H21NO2/c1-5-14(2,11-15(3)4)17-13(16)12-9-7-6-8-10-12/h6-10H,5,11H2,1-4H3Key: FDMBBCOBEAVDAO-UHFFFAOYSA-N
  • InChI=1/C14H21NO2/c1-5-14(2,11-15(3)4)17-13(16)12-9-7-6-8-10-12/h6-10H,5,11H2,1-4H3Key: FDMBBCOBEAVDAO-UHFFFAOYAQ
SMILES
  • O=C(OC(C)(CC)CN(C)C)c1ccccc1
Properties
Chemical formula C14H21NO2
Molar mass 235.32204
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Amylocaine was the first synthetic local anesthetic. It was synthesized and patented under the name Stovaine by Ernest Fourneau at the Pasteur Institute in 1903. It was formerly used mostly in spinal anesthesia.

Notes and references

  1. Fourneau is the French word for stove.
  2. "Stovaïne, anesthésique local", in Bull. Sc. pharmacolog., 1904, 10, 141.
  3. Christine Debue-Barazer, "Les implications scientifiques et industrielles du succès de la Stovaïne. Ernest Fourneau (1872-1949) et la chimie des médicaments en France", in Gesnerus 64, 2007, p. 25.

External links

Local anesthetics (primarily sodium channel blockers) (N01B)
Esters by acid
Aminobenzoic
Benzoic
ArCO2- (not para-amino or Ph)
Amides
Combinations
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