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| {{medref|date=April 2015}} | {{medref|date=April 2015}} | ||
| '''Scrambler therapy''' ( |
'''Scrambler therapy''' (sometimes '''Calmare scramber therapy''' or '''Calmare therapy''') involves the use of electronic stimulation on the skin with the goal of substituting pain information for non-pain information.<ref name="pachman2014" /> | ||
| It was invented by Giuseppe Marineo at the ].<ref name=inventor>Anson P National Pain Report 9 April 2014 </ref> The device used is a Calmare MC5-A device. It has been ]-cleared 510(k)-cleared and European ]-certified.<ref>http://calmaretherapynj.com/what-is-calmare</ref>{{npsn|date=April 2015}} | It was invented by Giuseppe Marineo at the ].<ref name=inventor>Anson P National Pain Report 9 April 2014 </ref> The device used is a Calmare MC5-A device. It has been ]-cleared 510(k)-cleared and European ]-certified.<ref>http://calmaretherapynj.com/what-is-calmare</ref>{{npsn|date=April 2015}} | ||
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| * mixed or neuropathic pain - 10/12 consecutive treatments of 30 or 45 minutes; once a day for five days a week. | * mixed or neuropathic pain - 10/12 consecutive treatments of 30 or 45 minutes; once a day for five days a week. | ||
| * cancer pain - initial treatment program consisting of 10/12 consecutive treatments of 45 minutes, once a day, and every time the pain reappears. Analgesia on patient request. | * cancer pain - initial treatment program consisting of 10/12 consecutive treatments of 45 minutes, once a day, and every time the pain reappears. Analgesia on patient request. | ||
| Research on the efficacy of scrambler therapy has had mixed results.<ref name="rivera2015" /><ref name="pachman2014">{{cite journal | author = Pachman, D. R., Watson, J. C., & Loprinzi, C. L. | year = 2014 | title = Therapeutic Strategies for Cancer Treatment Related Peripheral Neuropathies | journal = Current Treatment Options in Oncology | volume = 15 | issue = 4 | page = 577}}</ref> ] studies have found some benefit for treating chemotherapy-induced ].<ref name="rivera2015" /> One ] controlled study found that scrambler therapy was more effective than guideline-based drug management for treating ].<ref name="rivera2015" /> However, a randomized, ] study found no benefit over a ] therapy.ref name="pachman2014" /><ref name="rivera2015">{{cite journal | author = Rivera, E., & Cianfrocca, M. | year = 2015 | title = Overview of neuropathy associated with taxanes for the treatment of metastatic breast cancer | journal = Cancer Chemotherapy and Pharmacology | volume = 75 | issue = 4 | pages = 659-670}}</ref> | |||
| ==References== | ==References== | ||
Revision as of 07:00, 8 April 2015
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Scrambler therapy (sometimes Calmare scramber therapy or Calmare therapy) involves the use of electronic stimulation on the skin with the goal of substituting pain information for non-pain information.
It was invented by Giuseppe Marineo at the University of Rome Tor Vergata. The device used is a Calmare MC5-A device. It has been FDA-cleared 510(k)-cleared and European CE mark-certified.
Treatment is adminstered as follows:
- mixed or neuropathic pain - 10/12 consecutive treatments of 30 or 45 minutes; once a day for five days a week.
- cancer pain - initial treatment program consisting of 10/12 consecutive treatments of 45 minutes, once a day, and every time the pain reappears. Analgesia on patient request.
Research on the efficacy of scrambler therapy has had mixed results. Uncontrolled studies have found some benefit for treating chemotherapy-induced peripheral neuropathy. One randomized controlled study found that scrambler therapy was more effective than guideline-based drug management for treating neuropathic pain. However, a randomized, double-blind study found no benefit over a placebo therapy.ref name="pachman2014" />
References
- ^ Pachman, D. R., Watson, J. C., & Loprinzi, C. L. (2014). "Therapeutic Strategies for Cancer Treatment Related Peripheral Neuropathies". Current Treatment Options in Oncology. 15 (4): 577.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - Anson P National Pain Report 9 April 2014 Inventor of Calmare Scrambler Tries to Block Sales
- http://calmaretherapynj.com/what-is-calmare
- Calmare - doctor Q&A
- ^ Rivera, E., & Cianfrocca, M. (2015). "Overview of neuropathy associated with taxanes for the treatment of metastatic breast cancer". Cancer Chemotherapy and Pharmacology. 75 (4): 659–670.
{{cite journal}}: CS1 maint: multiple names: authors list (link)